Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Advanced Research Centre (ARC) Level 5, Digital Chemistry University of Glasgow 11 Chapel Lane Glasgow G11 6EW Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
499. Electron density-based GPT for optimization and suggestion of host–guest binders
498. A programmable hybrid digital chemical information processor based on the Belousov-Zhabotinsky reaction
497. An integrated self-optimizing programmable chemical synthesis and reaction engine
496. Autonomous execution of highly reactive chemical transformations in the Schlenkputer
495. Universal chemical programming language for robotic synthesis repeatability
494. Bringing digital synthesis to Mars
493. An Autonomous Electrochemical Discovery Robot that Utilises Probabilistic Algorithms: Probing the Redox Behaviour of Inorganic Materials
492. Reaction Kinetics using a Chemputable Framework for Data Collection and Analysis
491. Assembly theory explains and quantifies selection and evolution
490. Digital design and 3D printing of reactionware for on demand synthesis of high value probes