Oded Livnah, Enrico A. Stura, Dana L. Johnson, Linda S.Mulcahy, Nicholas C. Wrighton, William J. Dower, Linda K. Jolliffe, and Ian A. Wilson (1996)
Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8Å.
Science 273:464-471.
The receptor was crystallized in complex with a cyclic peptide. A full crystallization paper is in preparation.
This is a project in collaboration with R. W. Johnson: Linda Jolliffe and Dana Johnson.
Oded Livnah has been responsible for the structure determination.
Two heavy atom derivatives: Mercury acetate and Uranyl Nitrate were used for phasing of the data.
Signal transduction
This project was carried out in the Ian Wilson Laboratory.