Cooke Group Research

Research at the present time focuses upon the design, synthesis and characterisation of  functional redox-active molecules, polymers and their assemblies.
Current themes include:
1. Supramolecular polymers
(i) Sambe, L.; Stoffelbach, F.; Lyskawa, J.; Delattre, F.; Fournier, D.; Bouteiller, L.; Charleux, B.; Cooke, G.; Woisel, P.  “Host-Guest Modulation of the Micellization of a Tetrathiafulvalene-Functionalized Poly(N-isopropylacrylamide)”. Macromolecules, 2011, 44, 6532.
(ii) Bigot, J.; Fournier, D.; Lyskawa, J.; Marmin, T.; Cazaux, F.; Cooke, G.; Woisel, P. “Synthesis of thermoresponsive phenyl- and naphthyl-terminated poly(NIPAM) derivatives using RAFT and their complexation with cyclobis(paraquat-p-phenylene) derivatives in water”. Polymer Chemistry, 2010, 1, 1024.
2. Micelles and vesicles
(i) Louisy, J.; Delattre, F.; Lyskawa, J.; Malfait, A.; MacLean, C. E.; Sambe, L.; Zhu, N.; Cooke, G.; Woisel, P. “Surfactant-mediated control of CBPQT4+-dialkoxynaphthalene complexation”. Chemical Communications 2011,  6819.
(ii) Bigot, J.; Charleux, B.; Cooke, G.; Delattre, F.; Fournier, D.; Lyskawa, J.; Sambe, L.; Stoffelbach, F.; Woisel, P. “Tetrathiafulvalene End-Functionalized Poly(N-isopropylacrylamide): A New Class of Amphiphilic Polymer for the Creation of Multistimuli Responsive Micelles”. Journal of the American Chemical Society, 2010, 132, 10796.
3. Biomimetic chemistry
(i) Agasti, S. S.; Caldwell, S.T.; Cooke, G.; Jordan, B. J.; Kennedy, A.; Kryvokhyzha, N.; Rabani, G.; Rana, S.; Sanyal, A.; Rotello, V. M. “Dendron-based model systems for flavoenzyme activity: towards a new class of synthetic flavoenzyme”. Chemical Communications, 2008, 4123.
(ii) Legrand, Y.-M.; Gray, M.; Cooke, G.; Rotello, V. M. “Model Systems for Flavoenzyme Activity: Relationships between Cofactor Structure, Binding and Redox Properties”. Journal of the American Chemical Society 2003, 125, 15789.
4. Molecular machines and devices
(i) Cooke, G.; Stoddart, J. F. et al. “Highly stable tetrathiafulvalene radical dimers in [3]catenanes”. Nature Chemistry, 2010, 2, 870.
(ii) Caldwell, S. T.; Cooke, G.; Fitzpatrick, B.; Long, D.-L.; Rabani, G.; Rotello, V. M. “A flavin-based [2]catenane”. Chemical Communications 2008,  5912.
5. Organic photovoltaics and light emitting diodes
Recent Grants:

EPSRC (GR/M32702) 
Tetrathiafulvalene Functionalised Receptors        
48K
EPSRC  (GR/S09197/01)
Electrochemically controlled smart  surfaces
183K
EPSRC (GR/C53056X/1) 
Electrochemically controlled polymers             
209K
EPSRC (EP/003679/1)
Dynamics of reactions at the surfaces of liquids  and self-assembled monolayers 388K
EPSRC (EP/E018211)
Applying contemporary physical organic chemistry to study redox controlled hydrogen bonding interactions 318K
EPSRC (EP/E036244)
Science and Innovation Award (Physical Organic Chemistry) 2.6M
EPSRC (EP/H021833/1)
Molecular-Metal-Oxide Nanoelectronics                 3.5M
EPSRC/NSF (EP/I00343X)
Synergistic tailoring of flavins and quantum  dots for solar cell applications
392K
BBSRC (BB/D526310/1)
Doctoral training grant
434K

Editorial
  1. Letters in Organic Chemistry (Editorial Advisory Board)
  2. Mini-Reviews in Organic Chemistry (Editorial Advisory Board)
  3. ISRN Organic Chemistry (Editorial Board)
Current Group:
Group Members Photo
Contact:
Professor Graeme Cooke, BSc (Hons), PhD, FRSC,
Glasgow Centre for Physical Organic Chemistry,
WestCHEM,
School of Chemistry,
University of Glasgow,
Glasgow,  G12 8QQ.
Email: Graeme.Cooke@Glasgow.ac.uk
Tel: 0141 330 5500
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