The Cronin Group

Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


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Complex molecules hold the secret to finding aliens

In a new paper published in Nature Communications, titled “Identifying molecules as biosignatures with assembly theory and mass spectrometry”, Cronin Group researchers describe Assembly Theory, a new way of quantifying molecular complexity, which can be used to determine if a molecule required a biological system to create it. The complexity of molecules was also measured experimentally through mass spectrometry fragmentation, opening the door for the creation of a life detection machine. Since Assembly Theory relies on molecular complexity alone, the life detection process is agnostic, with no assumptions that alien life will be chemically similar to life on Earth.

The paper is open access, and can be accessed on the Nature Communications website

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Prof. Leroy (Lee) Cronin

Prof Leroy (Lee) Cronin
Regius Chair of Chemistry
Advanced Research Centre (ARC)
Level 5, Digital Chemistry
University of Glasgow
11 Chapel Lane
Glasgow G11 6EW
Tel: +44 141 330 6650
Email: lee.cronin@glasgow.ac.uk

Latest Publications

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529. Chemputer and chemputation—A universal chemical compound synthesis machine

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528. Verification and execution of the scientific literature via chemputation augmented by large language models

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527. Chemical programming of kinase inhibitors in a modular chemputer-based system

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526. Organophosphonate Ligation Approach for the Controlled Assembly of Gigantic Polyoxometalate Clusters

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525. Spontaneous assemblies of gigantic polyoxomolybdates; from structure and properties to synthetic methods

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524. ElectroChemputer with integrated monitoring for programmable electrochemistry

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523. Achieving Operational Universality through a Turing Complete Chemputer

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522. AI-driven robotic crystal explorer for rapid polymorph identification

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521. Rapid Exploration of the Assembly Chemical Space of Molecular Graphs

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520. Programmable Microwaveable Chemistry in the Chemputer


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