The Cronin Group

Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


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Complex molecules hold the secret to finding aliens

In a new paper published in Nature Communications, titled “Identifying molecules as biosignatures with assembly theory and mass spectrometry”, Cronin Group researchers describe Assembly Theory, a new way of quantifying molecular complexity, which can be used to determine if a molecule required a biological system to create it. The complexity of molecules was also measured experimentally through mass spectrometry fragmentation, opening the door for the creation of a life detection machine. Since Assembly Theory relies on molecular complexity alone, the life detection process is agnostic, with no assumptions that alien life will be chemically similar to life on Earth.

The paper is open access, and can be accessed on the Nature Communications website

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Prof. Leroy (Lee) Cronin

Prof Leroy (Lee) Cronin
Regius Chair of Chemistry
Advanced Research Centre (ARC)
Level 5, Digital Chemistry
University of Glasgow
11 Chapel Lane
Glasgow G11 6EW
Tel: +44 141 330 6650
Email: lee.cronin@glasgow.ac.uk

Latest Publications

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520. Rapid Exploration of the Assembly Chemical Space of Molecular Graphs

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519. Programmable Microwaveable Chemistry in the Chemputer

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518. Utilizing Similarity Measures to Map Chemical Reactivity

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517. Automated Digital Discovery and Synthesis of CuO-Based Nanoparticle Heterostructures for Catalysis

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516. Universal peptide synthesis via solid-phase methods fused with chemputation

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515. Regulating the Assembly of γ-Cyclodextrin Host and Polyoxometalate-Based Guests toward Light-Responsive Hybrid Rotaxanes

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514. Natural-Language-Interfaced Robotic Synthesis for AI-Copilot-Assisted Exploration of Inorganic Materials

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513. Robotic exploration of amino-acid functionalised molybdenum blue polyoxometalate nanoclusters

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512. A programmable modular robot for the synthesis of molecular machines

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511. Compression of Molybdenum Blue Polyoxometalate Cluster Rings


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