The Cronin Group

Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


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Joint US-UK Solution wins NIH Integrated Challenge Prize

The teams of Prof Walker from Arizona State University and Prof Cronin from Glasgow University have won a challenge prize for innovative solutions working towards innovation in pain, opioid use disorder and overdose.

The joint team combines expertise in exploring chemical space using statistical methods (ASU) with a programmable chemical robot for molecular discovery and synthesis (GU). Their project proposes a solution called ‘Integrated Discovery Chemputer Toward Addiction Free Opiates (ChemOPs)’.

The challenge solution proposes an integrated solution that leverages the Glasgow-based programmable chemical robot, ‘the Chemputer’ for the design and discovery of new candidate molecules for drug discovery, using network approaches to exploring chemical space devised by the ASU team. The integrated system will link a chemical database with the generation of chemical code that will operate the Chemputer to then make the drug candidates.

The prize announcement can be found at https://ncats.nih.gov/aspire/2018ChallengeWinners#c5

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Prof. Leroy (Lee) Cronin

Prof Leroy (Lee) Cronin
Regius Chair of Chemistry
Advanced Research Centre (ARC)
Level 5, Digital Chemistry
University of Glasgow
11 Chapel Lane
Glasgow G11 6EW
Tel: +44 141 330 6650
Email: lee.cronin@glasgow.ac.uk

Latest Publications

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529. Chemputer and chemputation—A universal chemical compound synthesis machine

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528. Verification and execution of the scientific literature via chemputation augmented by large language models

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527. Chemical programming of kinase inhibitors in a modular chemputer-based system

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526. Organophosphonate Ligation Approach for the Controlled Assembly of Gigantic Polyoxometalate Clusters

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525. Spontaneous assemblies of gigantic polyoxomolybdates; from structure and properties to synthetic methods

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524. ElectroChemputer with integrated monitoring for programmable electrochemistry

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523. Achieving Operational Universality through a Turing Complete Chemputer

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522. AI-driven robotic crystal explorer for rapid polymorph identification

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521. Rapid Exploration of the Assembly Chemical Space of Molecular Graphs

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520. Programmable Microwaveable Chemistry in the Chemputer


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