Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Advanced Research Centre (ARC) Level 5, Digital Chemistry University of Glasgow 11 Chapel Lane Glasgow G11 6EW Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
520. Rapid Exploration of the Assembly Chemical Space of Molecular Graphs
519. Programmable Microwaveable Chemistry in the Chemputer
518. Utilizing Similarity Measures to Map Chemical Reactivity
517. Automated Digital Discovery and Synthesis of CuO-Based Nanoparticle Heterostructures for Catalysis
516. Universal peptide synthesis via solid-phase methods fused with chemputation
515. Regulating the Assembly of γ-Cyclodextrin Host and Polyoxometalate-Based Guests toward Light-Responsive Hybrid Rotaxanes
514. Natural-Language-Interfaced Robotic Synthesis for AI-Copilot-Assisted Exploration of Inorganic Materials
513. Robotic exploration of amino-acid functionalised molybdenum blue polyoxometalate nanoclusters
512. A programmable modular robot for the synthesis of molecular machines
511. Compression of Molybdenum Blue Polyoxometalate Cluster Rings