Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Advanced Research Centre (ARC) Level 5, Digital Chemistry University of Glasgow 11 Chapel Lane Glasgow G11 6EW Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
509. High-Nuclearity Polyoxometalate-Based Metal–Organic Frameworks for Photocatalytic Oxidative Cleavage of C−C Bond
508. Operational considerations for approximating molecular assembly by Fourier transform mass spectrometry
507. Reaction blueprints and logical control flow for parallelized chiral synthesis in the Chemputer
506. Experimentally measured assemblyindices are required to determine the threshold for life
505. Algorithm-driven robotic discovery of polyoxometalate-scaffolding metal–organic frameworks
504. Reaction: Programmable chemputable click chemistry
503. Rethinking pharma and biotech outsourcing: A call for data security and supply chain resilience
502. Delocalized, asynchronous, closed-loop discovery of organic laser emitters
501. Investigating and Quantifying Molecular Complexity Using Assembly Theory and Spectroscopy
500. Electron density-based GPT for optimization and suggestion of host–guest binders