Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Advanced Research Centre (ARC) Level 5, Digital Chemistry University of Glasgow 11 Chapel Lane Glasgow G11 6EW Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
536. Quantifying Directedness in Chemical Reaction Networks Using Assembly Theory
535. Molecular assembly as a universal biosignature measurable by mass spectrometry
534. Dimensional Evolution from a Giant Molybdenum-Red Cage-like {Mo200} to 1D Chains Enabling Ultrahigh Proton Conduction
533. Expanding polyoxopalladate diversity: Ce4+-containing structures and chiral lanthanide clusters
532. Mapping Evolution of Molecules across Biochemistry with Assembly Theory
531. Chemputer and chemputation—A universal chemical compound synthesis machine
530. Verification and execution of the scientific literature via chemputation augmented by large language models
529. Chemical programming of kinase inhibitors in a modular chemputer-based system
528. Organophosphonate Ligation Approach for the Controlled Assembly of Gigantic Polyoxometalate Clusters
527. Spontaneous assemblies of gigantic polyoxomolybdates; from structure and properties to synthetic methods