The Cronin Group

Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


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Joint US-UK Solution wins NIH Integrated Challenge Prize

The teams of Prof Walker from Arizona State University and Prof Cronin from Glasgow University have won a challenge prize for innovative solutions working towards innovation in pain, opioid use disorder and overdose.

The joint team combines expertise in exploring chemical space using statistical methods (ASU) with a programmable chemical robot for molecular discovery and synthesis (GU). Their project proposes a solution called ‘Integrated Discovery Chemputer Toward Addiction Free Opiates (ChemOPs)’.

The challenge solution proposes an integrated solution that leverages the Glasgow-based programmable chemical robot, ‘the Chemputer’ for the design and discovery of new candidate molecules for drug discovery, using network approaches to exploring chemical space devised by the ASU team. The integrated system will link a chemical database with the generation of chemical code that will operate the Chemputer to then make the drug candidates.

The prize announcement can be found at https://ncats.nih.gov/aspire/2018ChallengeWinners#c5

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Prof. Leroy (Lee) Cronin

Prof Leroy (Lee) Cronin
Regius Chair of Chemistry
Cronin Laboratory
School of Chemistry
Joseph Black Building
University of Glasgow
Glasgow G12 8QQ
Tel: +44 141 330 6650
Email: lee.cronin@glasgow.ac.uk

Latest Publications

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471. Formalising the pathways of life to using assembly spaces

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470. Engineering Highly Reduced Molybdenum Polyoxometalates via the Incorporation of d and f Block Metal Ions

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469. Effective Storage of Electrons in Water by the Formation of Highly Reduced Polyoxometalate Clusters

468. A Probabilistic Chemical Programmable Computer

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467. Digitizing Chemical Synthesis in 3D Printed Reactionware

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466. Hydrogen from water electrolysis

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465. Investigating the autocatalytically driven formation of Keggin-based polyoxometalate clusters

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464. Exploring the sequence space of unknown oligomers and polymers

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463. Exploring the Hidden Constraints that Control the Self-Assembly of Nanomolecular Inorganic Clusters

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462. Facile and Reproducible Electrochemical Synthesis of the Giant Polyoxomolybdates


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