The Cronin Group

Research in the Digital Chemistry group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.


Latest News

...
August 2022: Lee Cronin appears on mendelspod podcast

Lee Cronin has appeared on the mendelspod podcast, a life sciences podcast which aims to “create a space for probing conversations and deep insight into the topics and trends which shape the industry’s future and therefore our future as a species”. In the podcast, he discusses the implications and applications of assembly theory and his group’s work on chemputers.

The full podcast can be found on the mendelspod website.

...
July 2022: Cronin group automated validation of chemical synthesis literature published in Science

Cronin group research into the automated validation of chemical synthesis literature has been published in Science. In the paper, entitled “Digitization and validation of a chemical synthesis literature database in the ChemPU”, researchers generated a database of chemical reactions, including the XDL code required to run the reactions on robotic platforms. More than 50 of these entries were downloaded and run successfully on modular chemputers, and an open database was set up for the addition of new reactions. This work showcases a major step towards the digitization of chemistry.

The full …

See More
...
June 2022: Prof Cronin gives plenary talk at Swedish Chemical Society conference

Prof Cronin has given a plenary talk at the second national meeting of the Swedish Chemical society, in Linköping, Sweden. In his talk, entitled “Chemputers, Chemputation, and Chemputability”, Prof Cronin described his pioneering research on the digitization of chemistry using automated platforms.

...
May 2022: Chemical Computers Featured in New Scientist

Cronin Group work on the development of chemical computers has been featured in New Scientist. The article, which can be found on the New Scientist website, describes how chemistry can be used to do computation, showcasing some of the group’s recent work in solving simple problems using chemical reactions to encode information. This work could lead to new insights into how the brain works, as well as new techniques for solving computationally difficult problems.

...
March 2022: Lee Cronin Appears on Lex Fridman Podcast

Lee Cronin has appeared on the Lex Fridman podcast, in an episode entitled “Lee Cronin: Origin of Life, Aliens, Complexity, and Consciousness”. The four hour discussion covered topics ranging from consciousness and the origin of life, to UFOs and a universal programming language for Chemistry. The full podcast can be viewed on YouTube

...
February 2022: Chemistry Kicks Off in the ARC

Chemistry operations have now officially begun in the ARC (Advanced Research Centre), following a complex moving operation lasting 4 to 5 weeks. During this time, with the help of specialist engineers, the Digital Chemistry group successfully relocated 7 analytical instruments and 2 rapid prototyping 3D printers as well as many hundreds of items of small equipment and chemicals. The new bespoke space will allow the group to enhance existing research, as well as expanding into new and exciting areas.

...
January 2022: Digital Chemistry Moves to the ARC

The Digital Chemistry research group, led by Prof Cronin, is this week moving into the Advanced Research Centre (ARC), the University of Glasgow’s new flagship research facility. The Cronin group will occupy much of the 5th floor of the ARC, within a cutting edge, custom built space for Digital Chemistry research.

University Press Release

ARC website

Photo Credit: Keith Hunter

...
November 2021: Prof Cronin Featured in Discover Magazine

An online article has been published by Discover Magazine, showcasing the work of Prof Cronin and his research group. The article delves into Prof Cronin’s personal history, as well as discussing his current passion for automating chemistry and using his Chemputer technology to discover the origins of life and intelligence.

The article can be viewed on the Discover Magazine website.

...
October 2021: Dr Nicola Bell Selected for Crucible Leadership Development Programme

Dr Nicola Bell (Senior Researcher in the group) has been selected for the prestigious Crucible Leadership Development Programme. The annual event is designed to support Early Career Researchers in taking the next step in their careers by helping to develop meaningful collaborations, increase ambitions and boldness of funding applications. Nicola was selected from a pool of talented researchers from across the university and will attend events focused on collaboration, research communication and research creativity. …

See More
...
October 2021: Chemistry World: Exploiting evolution to explore chemical space shows promise for drug discovery

A Chemistry World article has been published describing recent Cronin Group work on the development of Assembly Theory, and it’s applications in predicting how products will evolve in chemical reactions. This work could lead to the development of new drugs through intelligently exploring chemical space by combining the assembly spaces of known molecules.

The full article can be viewed on the Chemistry World website.

...
September 2021: Joint US-UK Solution wins NIH NCATS Prize

Prof Cronin’s team, alongside collaborators including Prof Walker from Arizona State University, have won an NIH NCATS ASPIRE Reduction-to-Practice Challenge prize, which is awarded to projects that offer solutions for the current opioid crisis. The prize was awarded for their work on the Closed Loop Bio Assay-Chemputer for Next Generation Analgesics (BioChemputer). This is the second such prize that Profs Cronin and Walker have been awarded, following the award of an NIH integrated challenge prize in 2019.

Information on the prize and winners can be found on the NCATS website.

See More
...
August 2021: Cronin Group researchers feature in NASA short video on Universal Life Detection

Cronin Group researchers have appeared in a short video produced by NASA, describing their work on Assembly Theory and Universal Life Detection. In the video, Prof Cronin and other researchers working on the project describe how recent work in establishing an Assembly Index for molecular complexity, and detecting it experimentally using Mass Spectrometry, could be used to construct a universal life detector, which could detect the presence of biological molecules even if they are completely unlike those on Earth.

The video can be seen on YouTube, or on the NASA website.

See More
...
Prof. Leroy (Lee) Cronin

Prof Leroy (Lee) Cronin
Regius Chair of Chemistry
Cronin Laboratory
School of Chemistry
Joseph Black Building
University of Glasgow
Glasgow G12 8QQ
Tel: +44 141 330 6650
Email: lee.cronin@glasgow.ac.uk

Latest Publications

...

471. Formalising the pathways of life to using assembly spaces

...

470. Engineering Highly Reduced Molybdenum Polyoxometalates via the Incorporation of d and f Block Metal Ions

...

469. Effective Storage of Electrons in Water by the Formation of Highly Reduced Polyoxometalate Clusters

468. A Probabilistic Chemical Programmable Computer

...

467. Digitizing Chemical Synthesis in 3D Printed Reactionware

...

466. Hydrogen from water electrolysis

...

465. Investigating the autocatalytically driven formation of Keggin-based polyoxometalate clusters

...

464. Exploring the sequence space of unknown oligomers and polymers

...

463. Exploring the Hidden Constraints that Control the Self-Assembly of Nanomolecular Inorganic Clusters

...

462. Facile and Reproducible Electrochemical Synthesis of the Giant Polyoxomolybdates

Group Funders

...
...
...
...
...
...
...
...

Find us on

Copyright © 2005 - 2022 Prof Lee Cronin - The University of Glasgow
Joseph Black Building, University of Glasgow, Scotland, UK
Visitors: