Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Cronin Laboratory School of Chemistry Joseph Black Building University of Glasgow Glasgow G12 8QQ Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
442. A robotic prebiotic chemist probes long term reactions of complexifying mixtures
441. Identifying molecules as biosignatures with assembly theory and mass spectrometry
440. A molecular computing approach to solving optimization problems via programmable microdroplet arrays
439. Influence of the Contact Geometry and Counterions on the Current Flow and Charge Transfer in Polyoxometalate Molecular Junctions: A Density Functional Theory Study
438. Elucidating the Paramagnetic Interactions of an Inorganic-Organic Hybrid Radical-Functionalized Mn-Anderson Cluster
437. Automatic Generation of 3D-Printed Reactionware for Chemical Synthesis Digitization using ChemSCAD
436. Optimization of Formulations Using Robotic Experiments Driven by Machine Learning DoE
435. Digitizing Chemistry Using the Chemical Processing Unit: From Synthesis to Discovery
434. Convergence of multiple synthetic paradigms in a universally programmable chemical synthesis machine
433. Peptide sequence mediated self-assembly of molybdenum blue nanowheel superstructures