Research in the Cronin Group is motivated by the fascination for complex chemical systems, and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks.
The universal language to program the chemputer ‘Chemical Processing Unit: ChemPU’ has been published in Science. In this paper the team shows how chemical synthesis literature can be automatically translated and run on a robotic platform to synthesise the compound without the need for any manual steps. The expert chemist uses the system to translate the literature to the chemical code (XDL) and then error checks the code before running it on the robots. The system is universal and the software easy to use and available to try at https://croningroup.gitlab.io/chemputer/xdlapp/. CNBC also covered the digital chemistry breakthrough.
Prof Leroy (Lee) Cronin Regius Chair of Chemistry Advanced Research Centre (ARC) Level 5, Digital Chemistry University of Glasgow 11 Chapel Lane Glasgow G11 6EW Tel: +44 141 330 6650 Email: lee.cronin@glasgow.ac.uk
476. An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials
475. An autonomous portable platform for universal chemical synthesis
474. Robotic synthesis of peptides containing metal-oxide-based amino acids
473. Selection of assembly complexity in a space of tetrapeptides
472. Digitization and validation of a chemical synthesis literature database in the ChemPU
471. Formalising the pathways of life to using assembly spaces
470. Engineering Highly Reduced Molybdenum Polyoxometalates via the Incorporation of d and f Block Metal Ions
469. Effective Storage of Electrons in Water by the Formation of Highly Reduced Polyoxometalate Clusters
468. A Probabilistic Chemical Programmable Computer
467. Digitizing Chemical Synthesis in 3D Printed Reactionware